Enabling a New Level of Ion Mobility Intelligence
IonDX provides next-generation ion mobility technology to analyze biologic drugs from glycoproteins and CRISPR-Cas to mRNA and lipid nanoparticles
IMgenius
Accelerating the next generation of biologic drugs
Versatile
Soft ionization conditions allow native conformations of biomacromolecules to be studied, e.g., non-covalent protein complexes, high molecular weight aggregates, mRNA, glycoproteins, CRISPR-Cas, virus particles, lipid nanoparticles
Benchtop
IonDX’s patented ion mobility technology provides powerful analytical characterization in a very compact benchtop design.
Ion Mobility
IMgenius determines the mobility of a population of molecular ions as they travel through a gas under the influence of an electric field. Small ions have higher mobility than larger ions because they experience less drag as they travel through a gas.
Enabling a New Level of Ion Mobility Intelligence
MISSION
IonDX™ Inc., based in Monterey, CA is commercializing an advanced system to analyze biologic drugs. The current biotherapeutic development cost is extremely high, >$2.5B and 8-10 years to introduce one of these drugs into the market. Our technology aims to improve analytical quality and reduce this cost by implementing a highly informative, fast, and reproducible assay. Our patented ion mobility spectrometers can simultaneously measure five important attributes of protein-based drugs: drug concentration, purity, stability and structural conformation of these molecules. We produce quantitative and correlative measurement in <5 minutes with our bench-top instrument. The short time range is rapid enough to introduce it in bioprocess environment where other technologies are too slow and unreliable. IonDX’s technology, being amenable to other analytical interfaces and automation, can fit into typical biotherapeutic high-throughput workflows, providing unique capability to reduce time and effort to bring a biotherapeutic to market.
NSF SBIR AWARDS
2019
NSF’s SBIR Phase II awarded to IonDX on Sept 10, 2019 in support of ongoing development of our ion mobility spectrometer for macromolecular analysis.
2017
NSF SBIR Phase I awarded to IonDX for our next-generation stand-alone electrospray ion mobility spectrometer.
IonDX Library
Access scientfic posters describing IonDX technology
Your Electrospray Ion Mobility Experts
Decades of experience including development of a medical diagnostic test based on Electrospray Ion Mobility. We are ready for your analytical challenge.
Higher Order Structure Analysis
IonDx provides analytical instrumentation and services for electrospray ion mobility of singly charged protein ions. You get non-distorted higher order structure characterization of your proteins, nanoparticles, or even exosomes.
Expand Your Totality of Evidence
IonDX's biomolecule comparability studies give you the biophysical fingerprint you need for your biotherapeutic drug
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info@iondx.com